Designing and editing biology to understand life

We are a lab of inventors working at the intersection of biology, engineering, and AI to develop technologies for biological programming

Overview

We explore the biological diversity of nature and algorithmic diversity of computers to create new ways of improving human health and augmenting our bodies. We have invented technologies for RNA-guided biological design, AI foundation models, and next-generation gene and cell therapies.

To do this, our group draws from a palette of experimental and computational approaches including CRISPR-Cas, machine learning, large-scale bioinformatics, engineered viruses, single cell sequencing and screening, and protein engineering/design.

Our work has been supported by the Arc Institute, Vinod Khosla, Sam Altman, DARPA, the NIH Director's Early Independence Award, the National Institute on Aging, NIGMS, Dipanjan and Shashikala Deb, the Curci Foundation, Emergent Ventures, and the Rainwater Foundation.

Our lab is physically located at the Arc Institute in Stanford Research Park and the Innovative Genomics Institute at UC Berkeley, and additionally affiliated with the California Institute for Quantitative Biosciences (QB3), Berkeley Stem Cell Center, UC Berkeley-UCSF Graduate Program in Bioengineering, Center for Computational Biology and CCB PhD Program, and Biophysics Graduate Program.

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