Editing biology to understand life

We work at the intersection of bioengineering and genomics to invent new tools for understanding and treating genetic disorders.


The Hsu Lab aims to understand and manipulate the genetic circuits that control brain and immune cell function to improve human health. We explore the rich biological diversity of nature to create new molecular technologies for genome and transcriptome engineering, perturb complex cellular processes at scale, and develop next-generation gene and cell therapies. To do this, our group draws from a palette of technologies including CRISPR-Cas, engineered viruses, genome sequencing, massively parallel reporter assays, and pooled genetic screens.

Our work is supported by the University of California at Berkeley, the NIH Director's Early Independence Award, the National Institute on Aging, NIGMS, Dipanjan and Shashikala Deb, the Curci Foundation, Fastgrants, and the Rainwater Foundation. We are housed within the Innovative Genomics Institute.